Graphene oxide catalyzed one-pot oxidative-Pictet-Spengler cascade for the synthesis of tetrahydroisoquinoline

Goutham,A. R. KWeerasingh, R. L. P2026-09-182026-09-182026-05ISSN 1012 - 8999https://dr.ichemc.ac.lk/handle/123456789/482Abstract No: 2025_411 Page 40The Pictet–Spengler reaction is a key transformation for synthesizing tetrahydroisoquinoline (THIQ) heterocycles, a privileged scaffold with antimicrobial, anticancer, and neuroprotective propertiesen-USPictet–Spengler reactiontetrahydroisoquinoline (THIQ)graphene oxide (GO)one-pot cascadeGraphene oxide catalyzed one-pot oxidative-Pictet-Spengler cascade for the synthesis of tetrahydroisoquinolineArticle