Browsing by Author "Gunaratna,M. J"
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Item Exploring in vitro antioxidant and anti-inflammatory activities of fresh fruit of Garcinia quaesita(Institute of Chemistry Ceylon, 2022-06) Ekanayaka,K. S. J; Gunaratna,M. JGarcinia quaesita which is locally referred to as “Rath Goraka”, is an endemic species growing wild in the wet and intermediate zones of Sri Lanka. This species has been in use for a long period of time in Sri Lankan traditional medicine to treat various disease conditions.Item In-silico investigation on derivatives of (Z)-N-phenyl acetamidoximes as potential inhibitors against Helicobacter pylori(Institute of Chemistry Ceylon, 2022-06) Dissanayaka,D. M. P. M; Gunaratna,M. JHelicobacter pylori is a major cause of gastrointestinal diseases, including gastritis, gastric and duodenal ulceration, gastric carcinoma, and gastric cancer. Urease enzyme secreted by H. pylori, hydrolyses urea, generating ammonia which neutralizes stomach acid and create a suitable pH environment to the bacterium to survive and colonize in the stomach.Item Synthesis of 2-phenyl-3H-quinazolin-4-one derivatives(Institute of Chemestry Ceylon, 2026-05-02) Pathirana,K. P. D. H; Gunaratna,M. JDiabetes mellitus is a common endocrine disorder characterized by hyperglycemia, which is increasing steadily all over the world. Current medications have limitations due to lower efficacy and side effects