Browsing by Author "Perera,N.T"
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Item Synthesis and characterization of platinum complexes with ethylenediamine and diethylenetriamine sulphonamide ligands towards biological applications(Institute of Chemistry Ceylon, 2021-06) Hettige , L; Perera,I.C; Perera,N.TDiethylenetriamine and ethylenediamine are renowned tridentate and bidentate chelating ligands, and have been utilized to synthesize sulfonamide derivatized platinum complexes.Item Synthesis and characterization of sulfonamide derivatized di-(2-picolyl)amine ligands and their rhenium tricarbonyl complexes towards fluorescent imaging(Institute of Chemistry Ceylon, 2019-05) Darshani,T; Perera,I.C; Perera,N.TThe synthesis and characterization of four novel compounds are reported in this study; N(SO2 )(1-nap)dpa (L1), N(SO2 )(2-nap)dpa (L2), fac-[Re(CO)3 (N(SO2 )(1nap)dpa)]PF6 (C1), fac-[Re(CO)3 (N(SO2 )(2-nap)dpa)] PF6 (C2) to evaluate their application as imaging agents.Item Synthesis and characterization of trimethylbenzene and chlorobenzene derivatized platinum complexes towards biological applications(Institute of Chemistry Ceylon, 2023-06) Yasarathna,K. W. G. K. P; Perera,L.C; Fronczek,F.R; Perera,N.TSynthesis of metal-based complexes as potential therapeutic agents for diseases like cancer, arthritis is a recent topic of interest. With the intention of identifying novel drug leads with potential biological applications, novel platinum complexes; {[Pt(N(SO2 trimethylbenzene)dpa)Cl2 ] (C1) and [Pt(N(SO2 chlorobenzene)dpa)Cl2 ] (C2)}, derived from sulfonamide ligands; {N(SO2 trimethylbenzene) dpa (L1) and N(SO2 chlorobenzene)dpa (L2)} were synthesized. These compounds were characterized by 1H NMR, X-ray crystallography, FT-IR, UV-Vis and f luorescence spectroscopic methods.