Browsing by Author "Perera,T"

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Synthesis, characterization and biological studies of a novel naphthalenederivatized tridentate ligand and its fac-[Re(CO)3 L] complex as potential therapeutic agents for lung cancer
(Institute of Chemistry Ceylon, 2018-05) Darshani,T; Priyadarshani,V V; Samarakoon,S; Perera,I C; Perera,T
Re(I) compounds, among other organometallic compounds, have recently gained attention as potential anticancer agents. In this study, a novel tridentate ligand (N(SO2 )(1-nap)dien) derived from diethylenetriamine (dien) attached to a sulfonamide group, was synthesized in good yield (63% yield) and its net neutral Re(I) complex ([Re(CO)3 (N(SO2 )(1-nap)dien)]) synthesized by treating fac-[Re(CO)3 (H2 O)3 ]+ with the synthesized ligand. The compounds were characterized by X-ray diffraction studies, 1H NMR, FT-IR, UV-Vis and f luorescence spectroscopies.