Riboswitches as Therapeutics Targets

Abstract

Regulation of gene expression includes a wide range of mechanisms that are used by cells to control the production of specific gene products. It has long been recognized that organisms make extensive use of protein based control systems to regulate gene expression. In eukaryotes, the networks of protein signaling and gene control factors are very complex, where numerous factors typically work together to influence transcription, translation, mRNA processing/degradation and other mechanisms that control the levels of gene products in a cell