Browsing by Author "Azeem,A"

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    T he inhibition of acetylcholinesterase via synthetically viable coumarin derivatives
    (Institute of Chemistry Ceylon, 2018-05) Azeem,A; Ratnaweera, C; Udawatte,C.S
    Acetylcholinesterase is a serine hydrolase responsible for the hydrolysis of acetylcholine. The reversible inhibition of acetylcholinesterase can be useful in combating Alzheimer’s disease (AD). A computational study of the inhibition of acetylcholinesterase was conducted by performing Molecular Docking using a series of coumarin analogs generated by fragment based drug design methods.