Browsing by Author "Jayasundara,U.K"
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Item Determination of the oxalate ion concentration in green leafy vegetables(2019-05) Liyanage,J.V; Jayasundara,U.KKidney and gall stone diseases occurring in the urinary tract can be life threatening and are promoted by the existence of oxalic acid (oxalate ion) in green leafy vegetables. Plants that accumulate large quantities of oxalic acid generally contain high concentrations of oxalate ions and salts.Item Development of a new spectrophotometric method for the analysis of metformin hydrochloride in drugs administered to patients with type II diabetes(Institute of Chemistry Ceylon, 2019-05) Herath,H.M.M.B; Jayasundara,U.KDetermination of drug concentration is important, as a specific dose is needed to be administered to each patient. This dose is different from one person to another person since the effective dose (ED50 ) for one person could be deadly for another person. Therefore, it is very important to ensure that the drug has the correct amount of active ingredients present in any drug component administered to a patient as overdosing or underdosing may create critical consequences to the patient.Item Method development and validation of lipid lowering drug Atorvastatin using UV-Visible spectroscopy(Institute of Chemistry Ceylon, 2019-05) Kaushalya,P.V.N; Jayasundara,U.KWith the high risk for cardiovascular diseases, statin drugs have become the life saver for millions of people around the world. Atorvastatin Calcium is one of the most commonly used lipid lowering drugs. Since this drug has been extensively used, it is essential to know the exact active ingredient concentration as the dose itself might cause negative impact on the patients.