In-silico investigation on derivatives of (Z)-N-phenyl acetamidoximes as potential inhibitors against Helicobacter pylori

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dc.contributor.authorDissanayaka,D. M. P. M
dc.contributor.authorGunaratna,M. J
dc.date.accessioned2025-03-03T03:46:59Z
dc.date.available2025-03-03T03:46:59Z
dc.date.issued2022-06
dc.descriptionAbstract No: TC 43 Page 48
dc.description.abstractHelicobacter pylori is a major cause of gastrointestinal diseases, including gastritis, gastric and duodenal ulceration, gastric carcinoma, and gastric cancer. Urease enzyme secreted by H. pylori, hydrolyses urea, generating ammonia which neutralizes stomach acid and create a suitable pH environment to the bacterium to survive and colonize in the stomach.
dc.identifier.urihttps://dr.ichemc.ac.lk/handle/123456789/381
dc.language.isoen
dc.publisherInstitute of Chemistry Ceylon
dc.relation.ispartofseries39; 1
dc.subjectHelicobacter pylori
dc.subjectUrease enzyme
dc.subjectDerivatives of (Z)-N-phenyl acetamidoxime
dc.subjectIn silico
dc.subjectUrease inhibition
dc.titleIn-silico investigation on derivatives of (Z)-N-phenyl acetamidoximes as potential inhibitors against Helicobacter pylori
dc.typeArticle

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