Abstract
Permanent URI for this collectionhttps://dr.ichemc.ac.lk/handle/123456789/82
Browse
Recent Submissions
Item Harnessing the Power of Visible Light with GO-Ni-ZnO Nanohybrid Electrospun Polymeric Membranes for Improved Photocatalysis:(Institute of Chemistry Ceylon, 2025-05) Pasindu ,Viraj; Yapa,Piumika; Dabare,Sanduni; Munaweera,Imalka; Etampawala,Thusitha; Weerasekera,Manjula M; Attygalle,Dinesh; Amarasinghe,ShanthaPhotocatalysis exhibits considerable potential for a range of environmental, energy, and biomedical applications, especially when employing metal-doped nanoparticle systems like Ni-doped ZnO. By giving nanohybrid stability and structural support, graphene oxide (GO) enhances photocatalytic activities and increases its durability and resistance to photo- corrosion.Item Enhanced antimicrobial and anti-inflammatory properties of PCL metal-turmeric oleoresin and metal-curcumin nanohybrids(Institute of Chemistry Ceylon, 2025-05) Senanayake,Dinithi; Yapa, Piumika; Dabare,Sanduni; Weerasekera,Manjula M; Etampawala, Thusitha N.B; Sethunga, Maheshika; Attygalle, Dinesh; Amarasinghe, Shantha; Munaweera, ImalkaThe concern about microbial infections and antimicrobial resistance has now shifted towards designing sustainable biomaterials with greater therapeutic efficacy for hospitals and several biomedical applications, which involve the use of modern multifunctional nanomaterials that are currently being studied.Item Antifungal efficacy of metallic silica nanohybrids embedded in hydrogel formulations for enhanced dermatological applications(Institute of Chemistry Ceylon, 2025-05) Yapa,P. N; Munaweera,I; Weerasekera,.M.MFungal skin infections pose a significant and escalating global health threat, emphasizing the need for innovative therapeutic approaches.Item α-Amylase Inhibitory Activity of Fractions Separated from The Seed Extract of Syzygium cumini (L.) Skeels(Institute of Chemistry Ceylon, 2025-05) Fernando,T. T. L; Munasinghe,M. S. T; Silva,H. I. C. DeDiabetes mellitus (DM) ranks a world-wide metabolic disorder in which chronic hyperglycemia arises due to insulin dysfunction. Syzygium cumini, a plant with medicinal properties and a tradition of being used for diabetes in Sri Lanka, was then confirmed to have antidiabetic potential.Item Use of Aqueous Na2CO3 Systems for Inhibition of Corrosion of Grade 202 Stainless-steel(Institute of Chemistry Ceylon, 2025-05) Dewappriya,P. D. T. A; Revon,M. H. N; Priyantha,NCorrosion is a process that promotes damaging attack on a metal by chemical or electrochemical reaction with the environment it is exposed to. Corrosion has been driven its concern due to costly maintenance, and hence, inhibitors are needed to avoid this undesirable situation.Item Evaluation of Justicia adhatoda Linn. extract-loaded layered double hydroxide nanohybrid for sunscreen applications(Institute of Chemistry Ceylon, 2025-05) Gunaratne,W. A. S. B; Silva,H. I. C. DeSafety concerns regarding synthetic sunscreens have increased the demand for botanical alternatives rich in phytochemicals with natural photo-protectant properties. Layered double hydroxides (LDHs) offer biocompatibility, tunable composition, high anion- exchange capacity, and controlled release. This study focused on developing a plant extract-incorporated LDH nanohybrid and evaluating its photostability and antioxidant activity. Based on the UV blocking ability at UVA and UVB regions, J. adhatoda was selected.Item Investigation of catalytic properties of green synthesized copper oxide nanoparticles in Biginelli reaction(Institute of Chemistry Ceylon, 2025-05) Perera,P. A. S. H; silva,H. I. C. DeBiginelli-type synthesis is an efficient one-pot synthesis method for preparation of 3,4-dihydroxypyrimidine derivatives, which have many pharmaceutical properties.Item Formulation of Psidium guajava Linn essential oil encapsulated solid lipid nanoparticles and evaluation of its anti-inflammatory and antioxidant activity(Institute of Chemistry Ceylon, 2025-05) Lakmali,M. G. C; Silva,H. I. C. DeEssential oils (EOs) possess significant therapeutic properties but are limited by volatility, instability, and poor bioavailability. This study aimed to encapsulate Psidium guajava Linn EO within solid lipid nanoparticles (SLNPs) to enhance its stability and biological efficacy.Item Electrochemical Impedance Spectroscopy for Prediction of Corrosion Inhibition of CaO Nanoparticles toward Grade 202 Stainless-steel(Institute of Chemistry Ceylon, 2025-05) Revon,M. H. N; Priyantha,NGrade 202 Stainless Steel (SS Grade 202) offers excellent corrosion resistant characteristics under mild conditions due to the presence of a relatively high chromium percentage although it is an alloy rich in iron.Item Chitosan-Stabilized Silver Nanoparticles: Molecular Dynamics Simulation on the Stability and in-vivo Interactive Toxicity with Cadmium on an Aquatic Model Moina macrocopa(Institute of Chemistry Ceylon, 2025-05) Perera,D. P. D; Samarakoon H. M. T. R; Dahanayake J. N; Wickramarachchi S. RSilver nanoparticles (AgNPs) are a significant innovation in nanoscience, particularly for their potential applications in biological systems. In this study, silver nanoparticles were synthesized using chitosan acting as both reducing and capping agent, and characterized by UV-visible spectroscopy,Item Antioxidant and photoprotective properties of Flacourtia indica fruit extract: fractionation, and application in lipstick formulation(Institute of Chemistry Ceylon, 2025-05) Dasanayaka,D. M. M. D; Rajapakse,C. S. KFlacourtia indica, known as Ugurassa in Sri Lanka, is widely recognized for its ethnomedicinal applications. Despite its traditional use, scientific studies on its antioxidant and photoprotective properties remain limited.Item Determination of the antibiotic amoxicillin in milk(Institute of Chemistry Ceylon, 2025-05) Salma,M. N. F; Nishshanka,O. K. D. U. P; Abeysinghe,D. TMilk proteins are among the most essential constituents of milk in terms of biological and nutritional properties. The use of antibiotics in food-producing animals causes the subsequent deposition of these drug residues in milk. Therefore, the quality of milk can be impaired due to antibiotics, leading to serious health concerns worldwide and in Sri Lanka, including antibiotic resistance and other adverse effects.Item Development of a value-added pumpkin (Cucurbita spp.) and curry leaves (Murraya koenigii) instant soup mixture and its proximate analysis.(Institute of Chemistry Ceylon, 2025-05) Silva,W. P. K. K de; Abeysinghe,D. TA healthy diet for humans should include a variety of foods, prioritizing providing a variety of nutrients. Nowadays, soup is considered a good food supplement due to its ability to provide a variety of nutrients, hydration, and support for digestion.Item Adsorptive removal of chromium (VI) from aqueous solutions using activated carbon derived from Calabash (Crescentia cujete) fruit shell(Institute of Chemistry Ceylon, 2025-05) Senevirathna, K.M; Prabagar,JHeavy metal contamination, particularly from hexavalent chromium [Cr(VI)], poses a significant environmental and health hazard due to its toxicity and persistence in aquatic systems.Item Nutritional and phytochemical profiling of Garcinia quaesita dried fruit rinds: a comparative study of commercially available samples in Sri Lanka(Institute of Chemistry Ceylon, 2025-05) Deepajith,U. L. P; Sakunthala, K. A. D. D; Perera,W. P. R. T; Abeysinghe,T; Liyanage,J.A; Premaratne, W. A. P. JT he fruit rind of Garcinia quaesita, commonly known as “Goraka” in Sri Lanka, has been utilized in Southeast Asia as a flavor enhancer and food preservative.Item Comparative analysis of nutritional and phytochemical properties of Murraya koenigii and Micromelum minutum cultivated in Sri Lanka(Institute of Chemistry Ceylon, 2025-05) Ranasingha,W. D. S. S. N; Sakunthala,K. A. D. D; Perera,W. P. R. T; Abeysinghe,T; Liyanage,J.A; Premaratne,W. A. P. JCurry leaves, native to Sri Lanka, Bangladesh, and India, are utilized as a flavoring agent and as a crucial component in Ayurvedic medicine.Item Synergistic enhancement of in-vitro cell migration by ethuliacoumarin and stigmasterol from Jeffreycia zeylanica:(Institute of Chemistry Ceylon, 2025-05) Samarasinghe,W.M.Priyantha; Gunaherath,G. M. Kamal B; Ranasinghe,Chandani ; Jayawardana,Kithsiri HectorScratch wound assay (SWA) directed fractionation of the hexane extract of aerial parts of J. zeylanica led to the isolation of ethuliacoumarin (1) and stigmasterol (2).Item Development of herbal tea from fruit peel of pomegranate cultivars grown in Sri Lanka(Institute of Chemistry Ceylon, 2025-05) Mirando M. D. J; Weerasooriya M. K. BPomegranate (Punica granatum L., family Punicaceae), is used in folklore medicine for the treatment of various diseases. Its peel is a valuable waste rich with a diverse range of bioactive compounds bearing significant antimicrobial, antioxidant, and anticancer activities.Item Metal Organic Framework Based Triboelectric Nanogenerator for Powering Electronics(Institute of Chemistry Ceylon, 2025-05) Sahu ,RojalinHarnessing mechanical energy from the surroundings shows significant promise as a power supply for micro and nanoscale devices. The functionality of the triboelectric nanogenerator (TENG) is based on the principles of triboelectrification and electrostatic inductionItem Modulation in the Structure, Dynamics, and Enzymatic Activity of an Ordered Protein β-Lactoglobulin through Liquid-Liquid Phase Separation(Institute of Chemistry Ceylon, 2025-05) Mukherjee ,SaptarshiBimolecular condensates formed through liquid–liquid phase separation (LLPS) of proteins, polypeptides, and nucleic acids have garnered significant research of late.1-3 Despite valuable contributions of prior research, there is untapped potential in exploring the influence of phase separation on the conformational dynamics and enzymatic activities of native proteins.