Synthesis, characterization and biological studies of a novel naphthalenederivatized tridentate ligand and its fac-[Re(CO)3 L] complex as potential therapeutic agents for lung cancer

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dc.contributor.authorDarshani,T
dc.contributor.authorPriyadarshani,V V
dc.contributor.authorSamarakoon,S
dc.contributor.authorPerera,I C
dc.contributor.authorPerera,T
dc.date.accessioned2025-02-28T04:56:06Z
dc.date.available2025-02-28T04:56:06Z
dc.date.issued2018-05
dc.descriptionpage 30,31 Technical Sessions : A - 24
dc.description.abstractRe(I) compounds, among other organometallic compounds, have recently gained attention as potential anticancer agents. In this study, a novel tridentate ligand (N(SO2 )(1-nap)dien) derived from diethylenetriamine (dien) attached to a sulfonamide group, was synthesized in good yield (63% yield) and its net neutral Re(I) complex ([Re(CO)3 (N(SO2 )(1-nap)dien)]) synthesized by treating fac-[Re(CO)3 (H2 O)3 ]+ with the synthesized ligand. The compounds were characterized by X-ray diffraction studies, 1H NMR, FT-IR, UV-Vis and f luorescence spectroscopies.
dc.identifier.urihttps://dr.ichemc.ac.lk/handle/123456789/359
dc.language.isoen
dc.publisherInstitute of Chemistry Ceylon
dc.relation.ispartofseries35; 2
dc.subjectSynthesis
dc.subjectcharacterization
dc.subjectbiological studies
dc.subjectnovel naphthalenederivatized
dc.subjectlung cancer
dc.titleSynthesis, characterization and biological studies of a novel naphthalenederivatized tridentate ligand and its fac-[Re(CO)3 L] complex as potential therapeutic agents for lung cancer
dc.typeArticle

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