Synergistic enhancement of in-vitro cell migration by ethuliacoumarin and stigmasterol from Jeffreycia zeylanica
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Date
2025-05
Journal Title
Journal ISSN
Volume Title
Publisher
Institute of Chemistry Ceylon
Abstract
Scratch wound assay (SWA) directed fractionation of
the hexane extract of aerial parts of J. zeylanica led to
the isolation of ethuliacoumarin (1) and stigmasterol
(2). These two compounds exhibited enhanced invitro cell migration activity each at 12.5 µM (1-67.0%
and 2-73.5%) compared to the negative control
(20.1%) in SWA performed on Madin-Darby Canine
Kidney (MDCK) cells.
Description
Abstract No: 2025_260
Page No 33
Keywords
Synergistic interaction, cell migration, ethuliacoumarin, stigmasterol, Jeffreycia zeylanica