Conference Abstracts
Permanent URI for this communityhttps://dr.ichemc.ac.lk/handle/123456789/2
News
Annual Sessions
Browse
Browsing Conference Abstracts by Title
Now showing 1 - 20 of 69
- Results Per Page
- Sort Options
Item A Computational Approach to Determine the Potential Inhibition of the Gomesin Peptide as an AKT1 Inhibitor in Breast Cancer(Institute of Chemistry Ceylon, 2023-06) Senapathi Tharindu; Selvaraj, Saranya; Weerasinghe, and LaksiriAnimal trials and in vitro drug screening can improve drug discovery. However, such pre-clinical screenings are often costly and time-consuming. Due to this, a more effective technique is developed using in silico method for the same.Item A novel immunoanalytical method for obesity biomarker detection using antibody functionalized silver nanoparticles(Institute of Chemistry Ceylon, 2019-05) Abeysinghe,A.A.D.T; Sirimuthu,N.M.S; Perera,P.P.RObesity is a serious health issue related with increased body fat content. Escalating numbers of patients have been reported worldwide throughout the recent past, associated with a high cost in the healthcare sector. Other than being a disease condition by itself, it also acts as a risk factor for many metabolic and cardiovascular diseases.Item A preliminary study on green synthesis of silver nanoparticles using Annona glabra leaf extract(Institute of Chemistry Ceylon, 2019-05) Sithara,W. S; Wickramarachchi,S; De Silva,C. R; Aberathna,A. A. A .U; Amarasinghe,L .DIn this study, an eco-friendly, simple, rapid and a cost effective biological method for reducing Ag+ ions into silver nanoparticles (AgNPs) using the leaf extract of Annona glabra (A. glabra) plant has been developed. Although a number of plant extract mediated synthesis of AgNPs have been reported in the literature no previous attempt has been made on the use of A. glabra in the green synthesis of AgNPs.Item A study on host-guest complexation of octaprotonated octaaza macrocycles with selected PAHs towards the template-directed synthesis of mechanically interlocked molecules(Institute of Chemistry Ceylon, 2023-06) Lekamge,Damith.D; Fernando,Isurika. RTemplate-directed synthesis (TDS) is one of the commonly used strategies in synthesis of mechanically interlocked molecules (MIMs). Inclusion complexes (ICs) of electron-deficient cationic macrocyclic ‘host’ and electron-rich ‘guest’ molecules have been used as donor-acceptor interactions driven ‘templates’ in TDS of MIMs.Item A study on the use of Bathophenanthroline as a fluorescence sensor for iron(II)(Institute of Chemistry Ceylon, 2019-05) Perera,P.P.P; De Costa,M D P; Senthilnithy,RAlthough Fe2+ is present as a trace element, it plays a vital role in living systems. Therefore measurement of trace amounts of Fe2+ is very important for many biological and ecological studies. Bathophenanthroline (BPhen) forms a stable 1:3 red color complex with Fe2+ and appears as a promising colorimetric probe for Fe2+. Using colorimetry, it has been possible to detect 10 parts of Fe2+ in 109 parts of water (540 nM).1,2Item Acute and subacute toxicity studies of the ethyl acetate soluble proanthocyanidins of immature inflorescence of Cocos nucifera L. in Wistar rats(Institute of Chemistry Ceylon, 2019-05) Ekanayake,C.P; Thammitiyagodage,M.G; Padumadasa,S; Seneviratne,B; Padumadasa,C; Abeysekera,A.MThe coconut palm, Cocos nucifera L. is a member of the monocotyledonous family, Arecaceae and mainly grows in tropical coastal areas. Ayurvedic and traditional medical practitioners of Sri Lanka use the decoction of the immature inflorescence of Cocos nucifera L. (IC) variety aurantiaca for the treatment of menorrhagiaItem Adsorptive removal of Co(II) in aqueous solutions using Strychnos potatorum seed powder(Institute of Chemistry Ceylon, 2019-05) Ranaweera,K. H; Perera,B. AContamination of natural water bodies due to improper discharge of heavy metals has become a worldwide environmental problem. Development of low cost adsorbent materials for the removal of heavy metals, utilizing the technique of adsorption is an effective solution to this problem.Item Agro-waste mediated nanomaterials for potential applications(Institute of Chemistry Ceylon, 2023-06) Thiripuranathar GobikaItem Antioxidant and antimicrobial activity of flower and leaf extracts of Calotropis gigante(Institute of Chemistry Ceylon, 2024-06) Kumari ,P.K.R.S; Edirisinghe,E.M.R.K.BCalotropis gigantea is latex bearing medicinal plant belonging to the family Apocynaceae. Two forms of C. gigantea; white-flowered form and purple-flowered form can be found native to Sri Lanka.Item Application of green synthesized palladium nanoparticles using banana leaf extract in Suzuki cross-coupling reaction(Institute of Chemistry Ceylon, 2019-05) Dantanarayana,S.O.A; De Silva,H.I.CApplication of plant extract-based nanoparticles in organic synthesis has become an emerging field today due to its biocompatibility, eco-friendliness and cost efficiency.1,2 The objectives of the present study were to develop an elementary and ecological method to synthesize palladium nanoparticles (Pd NPs) using extracts of banana leaves, which is a commonly found agro-waste in Sri Lanka, and investigate the catalytic activity of the synthesized Pd NPs in Suzuki crosscoupling reactions.Item Binding interactions of coumarin derivatives with Hodgkin’s disease related protein ADAM-10; an in-silico approach(Institute of Chemistry Ceylon, 2019-05) Thilakarathne,N.M. H. N; Udawatte,C. S; Rathnaweera,C .NHodgkin’s disease is a malignant tumor which is one of the most common cancers among the elderly and children. It is characterized by the overexpression of ADAM-10 protein with increased release of NKG2D ligand which causes impaired immune response against tumor cells.1Item Characterization of some selected compost samples for the presence of microplastics and heavy metals associated with them(Institute of Chemistry Ceylon, 2021-06-01) Atugoda,Thilakshani; Piyumalia, Hansika; Vithanage,MeththikaMicroplastics are ubiquitous in terrestrial environments as land-based sources mainly contribute to their origin. Mismanagement of solid waste can contribute to heavy loads of microplastics, which is of serious concern in Sri LankaItem Chemical and microbiological contaminants and preservatives in commercially available tomato sauces(Institute of Chemistry Ceylon, 2019-05) Iqbal,F.N; Somapala,E. G; Perera,M; Deraniyagala,S.PTomato sauces are a part of the processed food industry which is currently amongst the fastest growing both for consumption and export making it a highly profitable industry. The present work was aimed to determine microbiological and some chemical parameters of commercially available tomato sauces.Item Chemical hydrolysis of shark liver oil to produce fatty acid extracts for nutraceutical applications(Institute of Chemistry Ceylon, 2023-06) Jayakody J.A.K.S , Edirisinghe E.M.R.K.B.Senevirathne, S. A. Senarathna LItem Chemical hydrolysis of shark liver oil to produce fatty acid extracts for nutraceutical applications(Institute of Chemistry Ceylon, 2023-06) Jayakody,J.A.K.S; Edirisinghe,E.M.R.K.B; Senevirathne,S.A; Senarathna,LFatty acids (FAs) play a substantial role in human health. Shark liver oil (SLO) is a rich source of FAs particularly of Omega-3 polyunsaturated fatty acids (PUFAs) including, Eicosapentaenoic acid (EPA) and Docosahexaenoic acid (DHA).Item Cinnamon wood as an adsorbant for the removal of Cu2+ from aqueous solutions(Institute of Chemistry Ceylon, 2019-05) Wijesekara,D.N; Udawatte,C.SHeavy metal water pollution remains one of the most harmful ecological and health issues globally, and Cu2+ is a common pollutant found in water bodies. Cinnamon (Cinnamomum verum or Cinnamomum zeylanicum) is native to Sri Lanka. Cinnamon wood is discarded as firewood, making it an ideal candidate as a locally available low cost adsorbent for Cu2+.Item Complexation between Fe2+ and 1,10-Phenanthrolin-5-amine and the quenching mechanism(Institute of Chemistry Ceylon, 2019-05) Wijesekera,G. I. P; De Costa,M.D. P; Senthilnithy,R1,10-Phenanthroline and its derivatives are very important chelating bidentate ligands for transition metal ions.1 From previous studies, it has been investigated that Fe2+ make stable complexes with 1,10-Phenanthroline and its derivatives.2Item Computational studies on flabelliferins and their bioactivities(Institute of Chemistry Ceylon, 2024-06) Manchanayake,N.K.T; Jaufer,Afnan.M; Keerthi,A.A.PFlabelliferins are bioactive compounds found in palmyrah (Borassus Flabellifer L.). They are reported to have antiarthritic, antibacterial, anticancer, antidiabetic, anti-inflammatory, antipyretic, antioxidant activities, and effective ATPase inhibitors.Item Cytotoxic potential and apoptotic effect of Barringtonia asiatica seed kernel against HepG2 cell line(Institute of Chemistry Ceylon, 2019-05) Paramasamy,R; Ekanayake,S; Samarakoon,S.RLiver cancer causes significant morbidity and mortality among humans worldwide due to lack of effective therapeutic strategies for control and treatment. According to World Health Organization, 7.5 % of male deaths in Sri Lanka are due to liver cancer and mortality rate due to liver cancer is increasing each year1.Item Determination of antioxidant activity, phenolic content and pH in wine prepared from local beet(Institute of Chemistry Ceylon, 2019-05) Gunasekara,S.R; Udawatte,C.S; Weliwegamage,U.S.KBeetroot (Beta Vulgaris) is a vegetable containing high amounts of biologically active compounds such as antioxidants, and polyphenols. It also contains vitamin C, fiber, inorganic nitrogen and anthocyanin, which have various health benefits. In this study, wine was prepared by fermenting beet, and the antioxidant activity, pH and total phenolic content of the wine was determined.