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Item Estimation of dissolved organic carbon in source and treated water to ascertain treatment efficiency and water safety with respect to trihalomethanes(Institute of Chemistry Ceylon, 2019-05) Ilangangedara,D; Navaratne,A.NThe use of chlorine as a disinfectant, although essential for pathogen control, leads to the halogenation of organic matter present in source water and produces trihalomethanes (THMs) and halo acetic acids1 which have been identified as mutagenic and carcinogenic agents.2 For this reason, the United States Environmental Protection Agency currently regulates THMs and halo acetic acids in drinking water.3 Therefore, it is necessary to optimise plant conditions to minimize dissolved organic carbon (DOC) content in drinking water.Item Estimation of dissolved organic carbon in source and treated water to ascertain treatment efficiency and water safety with respect to trihalomethanes(Institute of Chemistry Ceylon, 2019-05) Ilangangedara,D; Navaratne,A.NThe use of chlorine as a disinfectant, although essential for pathogen control, leads to the halogenation of organic matter present in source water and produces trihalomethanes (THMs) and halo acetic acids1 which have been identified as mutagenic and carcinogenic agents.2 For this reason, the United States Environmental Protection Agency currently regulates THMs and halo acetic acids in drinking water.3Item Synthesis and evaluation of a transition metal ion- selective f luorescence sensor(Institute of Chemistry Ceylon, 2019-05) Perera,M.K.B.K; Vithanarachchi,S.M; Wijesekera,R.DHeavy metals are a common pollutant of the environment. Some of these metals can be toxic and hence, developing methods to detect their presence is important. Fluorescent chemosensors are available for detection of these metal ions. However, some of them have limitations such as low sensitivity, variations in sensitivity at different pH, and low solubility in aqueous systems.1Item Synthesis and characterization of sulfonamide derivatized di-(2-picolyl)amine ligands and their rhenium tricarbonyl complexes towards fluorescent imaging(Institute of Chemistry Ceylon, 2019-05) Darshani,T; Perera,I.C; Perera,N.TThe synthesis and characterization of four novel compounds are reported in this study; N(SO2 )(1-nap)dpa (L1), N(SO2 )(2-nap)dpa (L2), fac-[Re(CO)3 (N(SO2 )(1nap)dpa)]PF6 (C1), fac-[Re(CO)3 (N(SO2 )(2-nap)dpa)] PF6 (C2) to evaluate their application as imaging agents.Item A novel immunoanalytical method for obesity biomarker detection using antibody functionalized silver nanoparticles(Institute of Chemistry Ceylon, 2019-05) Abeysinghe,A.A.D.T; Sirimuthu,N.M.S; Perera,P.P.RObesity is a serious health issue related with increased body fat content. Escalating numbers of patients have been reported worldwide throughout the recent past, associated with a high cost in the healthcare sector. Other than being a disease condition by itself, it also acts as a risk factor for many metabolic and cardiovascular diseases.Item Determination of the solute descriptors for ethyl cinnamate by gas chromatography and liquid-liquid partition systems(Institute of Chemistry Ceylon, 2021-06) Hewage,K. P; Ariyasena,J. A. T. CEthyl cinnamate is a naturally occurring ester found in cinnamon oil extracts. Due to its fruity and balsamic odor, it is used in the preparation of artificial flavours of strawberry, raspberry and cherry and used in oriental oil perfumes.Item Optimization of Proteomics-based Substrate Trapping with Histone Deacetylase 1(Institute of Chemistry Ceylon, 2021-06) Herath, Kavinda E; Pflum,Mary Kay. HHistone writers and erasures – the proteins that add or remove histone post translational modifications – are key drivers of epigenetic transcriptional events inside the cell.Item Synthesis of Precursors of Cycloparaphenylenes Using Ullmann Coupling(Institute of Chemistry Ceylon, 2021-06) Edirisinghe,Lashan. G; Fernando,Isurika. R[n]Cycloparaphenylenes ([n]CPPs) are carbon and hydrogen containing macrocycles which constitute of ‘n’ number of para-phenylene groups connected via 1,4-biphenyl ‒C‒C‒ linkages.Item Highly Efficient Hydrogen Evolution and Hydrazine Oxidation of Platinum via Tuning the Interfacial Dissolved-Gas Concentration(Institute of Chemistry Ceylon, 2021-06) Ranaweera,RuchirangaRegulating the dissolved-gas concentration at the electrode solution interface represents a promising universal strategy to achieve high efficiency towards gas evolution reactions. Here,Item Semisynthetic derivatization studies of the fungal metabolite phomasetin with activity against the human parasite Trichomonas vaginalis(Institute of Chemistry Ceylon, 2021-06) Peramuna,ThilinaTrichomonasis is the most prevalent sexually transmitted parasitic disease (STD) in the United States and is caused by Trichomonas vaginalis.Item Synthesis and characterization of platinum complexes with ethylenediamine and diethylenetriamine sulphonamide ligands towards biological applications(Institute of Chemistry Ceylon, 2021-06) Hettige , L; Perera,I.C; Perera,N.TDiethylenetriamine and ethylenediamine are renowned tridentate and bidentate chelating ligands, and have been utilized to synthesize sulfonamide derivatized platinum complexes.Item Invasive plant-derived biochar for sorptive removal of hexavalent chromium in aqueous media(Institute of Chemistry Ceylon, 2021-06) Ekanayake,Anusha; Rajapaksha,Anushka. U; Vithanage,MeththikaDue to increased industrialization and urbanization, chromium (Cr) has been commonly used and released to the environment in a variety of industrial activities. Two primarily available valence states of chromium in the environment are trivalent chromium (Cr III) and hexavalent chromium (Cr VI). Cr(VI) is more soluble in water, causing health hazards to human beings and animals by all exposure rootsItem Semisynthetic derivatization studies of the fungal metabolite phomasetin with activity against the human parasite Trichomonas vaginalis(Institute of Chemistry Ceylon, 2021-06) Peramuna,ThiliniTrichomonasis is the most prevalent sexually transmitted parasitic disease (STD) in the United States and is caused by Trichomonas vaginalis.Item Characterization of some selected compost samples for the presence of microplastics and heavy metals associated with them(Institute of Chemistry Ceylon, 2021-06-01) Atugoda,Thilakshani; Piyumalia, Hansika; Vithanage,MeththikaMicroplastics are ubiquitous in terrestrial environments as land-based sources mainly contribute to their origin. Mismanagement of solid waste can contribute to heavy loads of microplastics, which is of serious concern in Sri LankaItem Sustainable production of nanomaterials and their activities(Institute of Chemistry Ceylon, 2022-06) Thiripuranathar,GobikaAgriculture is the mainstay of the livelihoods of Sri Lankans. Over the years, the horticulture sector, which includes fruits and vegetables, has gained significant importance and is identified as one of the major contributors to the agriculture sectorItem Improving the Stability of XLAsp-P2 Through Nano conjugation(Institute of Chemistry Ceylon, 2022-06) Amarasekara,Yasuri D.EAntimicrobial (AMP) and Anti-cancer peptides (ACPs) recently have received significant attention as promising chemotherapeutic agents that avoid the drawbacks of current drugs.Item A Computational Approach to Determine the Potential Inhibition of the Gomesin Peptide as an AKT1 Inhibitor in Breast Cancer(Institute of Chemistry Ceylon, 2023-06) Senapathi Tharindu; Selvaraj, Saranya; Weerasinghe, and LaksiriAnimal trials and in vitro drug screening can improve drug discovery. However, such pre-clinical screenings are often costly and time-consuming. Due to this, a more effective technique is developed using in silico method for the same.Item Qualitative and quantitative detection of peanut oil adulteration in sesame oil(Institute of Chemistry Ceylon, 2023-06) Kathirgamanathar,Selvaluxmy; Sahara,B.A.W; Gunasekara,M.M.N.P; Wijeyasiriwardena,T.D.C.M.KT he present study was focused on developing rapid, costeffective, and straightforward methods for qualitative and quantitative detection of peanut oil (PO) adulteration in sesame oil (SO). In Sri Lanka, due to the higher price and demand of SO, merchants intentionally add cheaper and lower quality edible oils mainly the PO foreconomic gains.Item Evaluation of the anti-inflammatory activity and bioactive compounds of Citrus aurantifolia(L) leaf extracts(Institute of Chemistry Ceylon, 2023-06) Jagoda,D; Liyanaarachchi,G.D; Weeratunge,H.D; Handunnetti,Shiroma. M; Fernando,Narmada; Samarasekara,J.K.R.RCitrus aurantifolia L. is used in traditional systems of medicine as remedy for stomach ailments, constipation, headache, arthritis, colds, coughs, sore throats, and appetite stimulant.Item Modification of Sri Lankan vein graphite with copper (II) oxide on silicon dioxide to enhance the photocatalytic dye-degradation(Institute of Chemistry Ceylon, 2023-06) Ravichandran,Myuraanjali; Jayawardena,SavidyaOne of the major issues with water contamination is related to the wastewater discharged by the textile industry which releases approximately 20% of the dye produced worldwide as waste into industrial effluents. The dyes in wastewater are highly stable, coloured pigments that cause serious disruption to aquatic ecology.